Cashing In on ATM to Repair DNA Damage

摘要

With so much modern molecular biology utterly dependent on mutations of various kinds it is easy to lose sight of how faithful DNA duplication is normally. Millions upon millions of base pairs are copied accurately for every mistake, and damage to the DNA is generally repaired before it can do real damage to the cell. At #3 in the current Top Ten is a paper elucidating a crucial component in the system that repairs potentially the most destructive damage of all, double-stranded breaks.