Anti-MDA5 antibody, ferritin and IL-18 are useful for the evaluation of response to treatment in interstitial lung disease with anti-MDA5 antibody-positive dermatomyositis

Takahisa Gono1 Shinji Sato2 Yasushi Kawaguchi1 Masataka Kuwana3 Masanori Hanaoka1 Yasuhiro Katsumata1 Kae Takagi1 Sayumi Baba1 Yuko Okamoto1 Yuko Ota1 and Hisashi Yamanaka1

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Anti-MDA5 antibody, ferritin and IL-18 are useful for the evaluation of response to treatment in interstitial lung disease with anti-MDA5 antibody-positive dermatomyositis

机译：抗MDA5抗体，铁蛋白和IL-18可用于评估抗MDA5抗体阳性的皮肌炎对间质性肺疾病的治疗反应

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Objective. The aim of this study was to investigate the precise clinical characteristics and to analyse the association between the anti-MDA5 antibody (anti-MDA5ab) titre and disease status in patients with anti-MDA5ab-positive DM.

机译：目的。这项研究的目的是调查精确的临床特征，并分析抗MDA5ab阳性DM患者的抗MDA5抗体（抗MDA5ab）滴度与疾病状况之间的关系。

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《Rheumatology》 |2012年第9期|p.1563-1570|共8页
作者
Takahisa Gono1 Shinji Sato2 Yasushi Kawaguchi1 Masataka Kuwana3 Masanori Hanaoka1 Yasuhiro Katsumata1 Kae Takagi1 Sayumi Baba1 Yuko Okamoto1 Yuko Ota1 and Hisashi Yamanaka1;
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1Institute of Rheumatology, Tokyo Women's Medical University, Tokyo, 2Division of Rheumatology, Department of Internal Medicine, Tokai University School of Medicine, Isehara and 3Division of Rheumatology, Department of Internal Medicine, Keio University School of Medicine, Tokyo, Japan.;

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1. Anti-MDA5 antibody, ferritin and IL-18 are useful for the evaluation of response to treatment in interstitial lung disease with anti-MDA5 antibody-positive dermatomyositis [J] . GonoT., SatoS., KawaguchiY., Rheumatology . 2012,第9期

机译：抗MDA5抗体，铁蛋白和IL-18可用于评估抗MDA5抗体阳性的皮肌炎对间质性肺疾病的治疗反应
2. Limitations of a single-point evaluation of anti-MDA5 antibody, ferritin, and IL-18 in predicting the prognosis of interstitial lung disease with anti-MDA5 antibody-positive dermatomyositis. [J] . Yoshinao Muro, Kazumitsu Sugiura, Masashi Akiyama Clinical rheumatology . 2013,第3期

机译：抗MDA5抗体，铁蛋白和IL-18的单点评估在预测抗MDA5抗体阳性皮肌炎的间质性肺疾病预后中的局限性。
3. Serum neopterin as well as ferritin, soluble interleukin-2 receptor, KL-6 and anti-MDA5 antibody titer provide markers of the response to therapy in patients with interstitial lung disease complicating anti-MDA5 antibody-positive dermatomyositis [J] . Nishioka Aki, Tsunoda Shinichiro, Abe Takeo, Modern rheumatology . 2019,第5期

机译：血清Neopterin以及铁蛋白，可溶性白细胞介素-2受体，Kl-6和抗MDA5抗体滴度提供对抗体肺病患者的治疗反应的标志物，其复制抗MDA5抗体阳性Dermatomyisis
4. Interstitial Lung Diseases/Diffuse Parenchymal Lung Diseases in Dogs and Cats [C] . American College of Veterinary Internal Medicine Forum Conference . 2018

机译：狗和猫的间质性肺病/弥漫性实质肺病
5. Occupational Exposures and Subclinical Interstitial Lung Disease: The Mesa (Multi-Ethnic Study of Atherosclerosis) Air-Lung Study [D] . Sack, Coralynn. 2018

机译：职业暴露与亚临床间质性肺病：梅萨（动脉粥样硬化的多民族研究）空气肺研究
6. Successful Treatment of Anti-MDA5 Antibody-Positive Dermatomyositis-Associated Rapidly Progressive-Interstitial Lung Disease by Plasma Exchange: Two Case Reports [O] . Rina Takahashi, Tadashi Yoshida, Kohkichi Morimoto, 2021

机译：通过等离子体交换成功治疗抗MDA5抗体阳性皮肤病患者相关的快速进展 - 间质性肺病：两种报告
7. The Serum Ferritin Level Is Associated with the Treatment Responsivity for Rapidly Progressive Interstitial Lung Disease with Amyopathic Dermatomyositis, Irrespective of the Anti-MDA5 Antibody Level [O] . Takeshi Osawa, Kozo Morimoto, Yuka Sasaki, 2018

机译：无论抗MDA5抗体水平如何，血清铁蛋白水平与快速渐进式间质性肺病的治疗响应性有关，无论抗MDA5抗体水平如何

Anti-MDA5 antibody, ferritin and IL-18 are useful for the evaluation of response to treatment in interstitial lung disease with anti-MDA5 antibody-positive dermatomyositis

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