Conformation of Di-N-Propyl Glycine Residue in a Glycine Rich Peptide Sequence

Kalpana Bhargava R. Balaji Rao

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Conformation of Di-N-Propyl Glycine Residue in a Glycine Rich Peptide Sequence

机译：富含甘氨酸的肽序列中的二-N-丙基甘氨酸残基的构象

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摘要

The peptide Boc-(Gly-Dpg-Gly)3-OBzl (I) has been synthesized to examine the conformational preferences of Dpg residues in a peptide sequence rich in glycine, which is known to be a poor helix promoter. The detailed NMR studies revealed that peptide (I) adopts a helical conformation in CDCl3.

机译：已经合成了肽Boc-（Gly-Dpg-Gly）3-OBzl（I），以检查富含甘氨酸的肽序列中Dpg残基的构象偏好，已知该序列是不良的螺旋启动子。详细的NMR研究表明，肽（I）在CDCl3中采用螺旋构象。

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《Protein and Peptide Letters》 |2001年第4期|p.307-315|共9页
作者
Kalpana Bhargava R. Balaji Rao;
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作者单位

Department of Chemistry, Banaras Hindu University, Varanasi-221005, India.;

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原文格式 PDF
正文语种 eng
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关键词
Propyl Glycine, Glycine Rich Peptide;

机译：丙基甘氨酸;富含甘氨酸的肽;

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专利

1. Conformation of Di-n-propyl glycine residue in a glycine rich peptide sequence [J] . Kalpana Bhargava, R. Balaji Rao Protein and peptide letters . 2001,第4期

机译：富含甘氨酸的肽序列中二正丙基甘氨酸残基的构象
2. Solution conformation of a tetradecapeptide stabilized by two di-n-propyl glycine residues [J] . Sarojini V., Rao R.B., Ragothamad S., Journal of peptide science: An official publication of the European Peptide Society . 2010,第8期

机译：由两个二正丙基甘氨酸残基稳定的四肽的溶液构象
3. Stereochemical Analysis of Higher α ,α -Dialkylglycine Containing Peptides. Characterization of Local Helical Conformations at Dipropylglycine Residues and Observation of a Novel Hydrated Multiple β-Turn Structure in Crystals of a Glycine Rich Pe [J] . Isabella L. Karle, Ramesh Kaul, R. Balaji Rao Journal of the American Chemical Society . 1997,第50期

机译：含较高级α，α-二烷基甘氨酸的肽的立体化学分析。二丙基甘氨酸残基上的局部螺旋构象的表征以及富含甘氨酸的Pe晶体中新型水合多重β-转角结构的观察
4. Microwave-Assisted Synthesis of a Glycine-Rich Difficult Peptide Sequence, the C-terminal Amidated Portion of Acanthoscurrin [C] . Vinicius M.R. Milan, Diego P. Santos, Marda L.A. Temperini American Peptide Symposium . 2011

机译：微波辅助合成富含甘氨酸的难肽序列，C-末端酰胺化部分的Acanthoscurrin
5. Asymmetric synthesis of stereochemically-defined and conformationally-constrained novel amino acids via direct alkylation of chiral nickel(II)-coordinated Schiff bases of glycine and alanine, and design and synthesis of selective peptide and non-peptide ligands for the delta-opioid receptor. [D] . Tang, Xue-jun. 2002

机译：通过手性镍（II）配位的甘氨酸和丙氨酸的席夫碱直接烷基化的立体化学定义和构象约束的新型氨基酸的不对称合成，以及δ阿片受体的选择性肽和非肽配体的设计和合成。
6. Suppressor analysis of mutations in the loop 2-3 motif of lactose permease: evidence that glycine-64 is an important residue for conformational changes. [O] . A E Jessen-Marshall, N J Parker, R J Brooker 1997

机译：乳糖通透酶环2-3环基序突变的抑制子分析：证据表明甘氨酸64是构象变化的重要残基。
7. Selective antimicrobial activity and mode of action of adepantins, glycine-rich peptide antibiotics based on anuran antimicrobial peptide sequences. [O] . Ilić N, Novković M, Guida F, 2013

机译：基于阿努兰抗菌肽序列的阿德潘丁（富含甘氨酸的肽抗生素）的选择性抗菌活性和作用方式。

Conformation of Di-N-Propyl Glycine Residue in a Glycine Rich Peptide Sequence

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