首页> 外文期刊>Proceedings of the National Academy of Sciences of the United States of America >A mouse atlas of gene expression: large-scale digital gene-expression profiles from precisely defined developing C57BL/6J mouse tissues and cells.
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A mouse atlas of gene expression: large-scale digital gene-expression profiles from precisely defined developing C57BL/6J mouse tissues and cells.

机译:基因表达的小鼠图谱:精确定义的发育中的C57BL / 6J小鼠组织和细胞的大规模数字基因表达谱。

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摘要

We analyzed 8.55 million LongSAGE tags generated from 72 libraries. Each LongSAGE library was prepared from a different mouse tissue. Analysis of the data revealed extensive overlap with existing gene data sets and evidence for the existence of approximately 24,000 previously undescribed genomic loci. The visual cortex, pancreas, mammary gland, preimplantation embryo, and placenta contain the largest number of differentially expressed transcripts, 25% of which are previously undescribed loci.
机译:我们分析了从72个库生成的855万个LongSAGE标签。每个LongSAGE库均从不同的小鼠组织中制备。数据分析显示与现有基因数据集广泛重叠,并且证据表明存在大约24,000个先前未描述的基因组基因座。视觉皮层,胰腺,乳腺,植入前胚胎和胎盘包含数量最多的差异表达转录本,其中25%是以前未描述的基因座。

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