The drugs don't work

摘要

ALZHEIMER'S disease is back in the news, with last week's announcement that the annual Brain prize has been awarded for work on the genetic and molecular basis of the illness. In giving the €1 million prize to four researchers in the UK, Germany and Belgium, Denmark's Lundbeck Foundation is likely to rekindle hopes of a cure being within reach. However, translating the work - much of it in animals - into drugs remains as frustratingly out of reach as ever.