De novo and secondary anaplastic meningiomas: a study of clinical and histomolecular prognostic factors

Peyre Matthieu; Gauchotte Guillaume; Giry Marine; Froehlich Sebastien; Pallud Johan; Graillon Thomas; Bielle Franck; Cazals-Hatem Dominique; Varlet Pascale; Figarella-Branger Dominique; Loiseau Hugues; Kalamarides Michel

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De novo and secondary anaplastic meningiomas: a study of clinical and histomolecular prognostic factors

机译：新生和继发性间变性脑膜瘤：临床和组织分子预后因素的研究

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Background. Following recent studies underlining the differences between de novo and secondary anaplastic meningiomas and the prognostic value of telomerase reverse transcriptase (TERT) promoter mutation, we decided to conduct a multicenter retrospective study to address these questions and determine specific prognostic factors in each of these 2 anaplastic meningioma subgroups.

机译：背景。最近的研究强调了新生和继发性间变性脑膜瘤之间的差异以及端粒酶逆转录酶（TERT）启动子突变的预后价值，我们决定进行多中心回顾性研究，以解决这些问题并确定这两种间变性中的每一个的特定预后因素脑膜瘤亚组。

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来源
《Neuro-Oncology》 |2018年第8期|1113-1121|共9页
作者
Peyre Matthieu; Gauchotte Guillaume; Giry Marine; Froehlich Sebastien; Pallud Johan; Graillon Thomas; Bielle Franck; Cazals-Hatem Dominique; Varlet Pascale; Figarella-Branger Dominique; Loiseau Hugues; Kalamarides Michel;
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作者单位

Grp Hosp Pitie Salpetriere, AP HP, Dept Neurosurg, Paris, France;

CHRU, U954, INSERM, Dept Pathol, Nancy, France;

Inst Cerveau & Moelle Epiniere, INSERM, Unit 1127, Paris, France;

Hop Lariboisiere, AP HP, Dept Neurosurg, Paris, France;

Hop St Anne, Dept Neurosurg, Paris, France;

Hop La Timone, Dept Neurosurg, Marseille, France;

Hop La Pitie Salpetriere, AP HP, Dept Neuropathol, Paris, France;

Hop Beaujon, Dept Neuropathol, Clichy, France;

Paris Descartes Univ, Sorbonne Paris Cite, Paris, France;

Aix Marseille Univ, La Timone Hosp, AP HM, Dept Pathol & Neuropathol,CRO2, Marseille, France;

Hop Pellegrin, Dept Neurosurg, Bordeaux, France;

Grp Hosp Pitie Salpetriere, AP HP, Dept Neurosurg, Paris, France;

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正文语种 eng
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关键词
anaplastic; grade 3; meningioma; prognosis; TERT;

机译：间变性;3级;脑膜瘤;预后;TERT;

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De novo and secondary anaplastic meningiomas: a study of clinical and histomolecular prognostic factors

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