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Immune to the facts

机译:对事实免疫

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摘要

The measles virus is remarkably contagious, infecting more than 95% of susceptible humans exposed to it. About 1 in 1,000 people infected requires hospitalization and may become permanently disabled, and 1 in 300,000 infected with measles develops a progressive neurological disorder, subacute sclerosing panencephalitis, which invariably causes death. But along with smallpox, yellow fever and poliomyelitis, measles is remarkably well controlled by vaccination. Before routine measles vaccination in the United States, some 4,000,000 people a year contracted the disease; widespread vaccination has brought this number down to less than 40. Other countries in which 95% of the population are vaccinated — the proportion believed to provide 'herd immunity', which blocks the transmission of measles—have experienced similar declines in cases. However, coverage in some regions of Africa is less than 50% of the population, and there are still some 40,000,000 infections each yrar, causing more than 600,000 deaths.
机译:麻疹病毒具有极强的传染性,感染超过95%的易感人群。大约每千名感染者中有1人需要住院治疗,并且可能会永久性残疾,而每300,000例麻疹感染者中会发展出一种进行性神经系统疾病,即亚急性硬化性全脑炎,这必然导致死亡。但是,除了天花,黄热病和小儿麻痹症外,接种疫苗还可以很好地控制麻疹。在美国进行常规麻疹疫苗接种之前,每年约有400万人感染该疾病;广泛的疫苗接种使这一数字下降到不到40个。在其他95%的人口进行了疫苗接种的国家(据信提供“群免疫”的比例,这阻止了麻疹的传播)的病例也有所减少。但是,非洲某些地区的覆盖率不到总人口的50%,每个年轻人仍然有大约4000万例感染,导致600,000多例死亡。

著录项

  • 来源
    《Nature》 |2004年第7015期|p.275-276|共2页
  • 作者

    Michael B. A. Oldstone;

  • 作者单位

    Division of Virology, Department of Neuropharmacology, The Scripps Research Institute, 10550 North Torrey Pines Road, La Jolla, California 92037, USA;

  • 收录信息 美国《科学引文索引》(SCI);美国《工程索引》(EI);美国《生物学医学文摘》(MEDLINE);美国《化学文摘》(CA);
  • 原文格式 PDF
  • 正文语种 eng
  • 中图分类 自然科学总论;
  • 关键词

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