Crystal structures of DNA/RNA repair enzymes AlkB and ABH2 bound to dsDNA

Cai-Guang Yang; Chengqi Yi; Erica M. Duguid; Christopher T. Sullivan; Xing Jian; Phoebe A. Rice; Chuan He

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Crystal structures of DNA/RNA repair enzymes AlkB and ABH2 bound to dsDNA

机译：与dsDNA结合的DNA / RNA修复酶AlkB和ABH2的晶体结构

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Escherichia coli AlkB and its human homologues ABH2 and ABH3 repair DNA/RNA base lesions by using a direct oxidative dealkylation mechanism. ABH2 has the primary role of guarding mammalian genomes against 1-meA damage by repairing this lesion in double-st

机译：大肠杆菌AlkB及其人类同源物ABH2和ABH3通过使用直接氧化脱烷基机制修复DNA / RNA碱基损伤。 ABH2的主要作用是通过双重修复该病灶来保护哺乳动物基因组免受1-meA损伤

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来源
《Nature》 |2008年第7190期|p.961-965|共5页
作者
Cai-Guang Yang; Chengqi Yi; Erica M. Duguid; Christopher T. Sullivan; Xing Jian; Phoebe A. Rice; Chuan He;
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作者单位

Department of Chemistry, The University of Chicago, 929 East 57th Street, Chicago, Illinois 60637, USA;

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收录信息美国《科学引文索引》(SCI);美国《工程索引》(EI);美国《生物学医学文摘》(MEDLINE);美国《化学文摘》(CA);
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正文语种 eng
中图分类自然科学总论;
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专利

1. Crystal structures of catalytic complexes of the oxidative DNA/RNA repair enzyme AlkB. [J] . Yu B, Edstrom WC, Benach J, Nature . 2006,第7078期

机译：氧化DNA / RNA修复酶AlkB的催化复合物的晶体结构。
2. Insights into RNA/DNA hybrid recognition and processing by RNase H from the crystal structure of a non-specific enzyme-dsDNA complex. [J] . Pallan PS, Egli M Cell cycle . 2008,第16期

机译：从非特异性酶-dsDNA复合物的晶体结构深入了解RNA酶H的RNA / DNA杂合识别和加工。
3. Crystal Structure and RNA Binding Properties of the RNA Recognition Motif (RRM) and AlkB Domains in Human AlkB Homolog 8 (ABH8), an Enzyme Catalyzing tRNA Hypermodification [J] . Chiara Pastore, Irini Topalidou, Farhad Forouhar, The Journal of biological chemistry . 2012,第3期

机译：RNA识别基序（RRM）和人ALKB同源物8（ABH8）中的RNA识别基序（RRM）和ALKB结构域的晶体结构和RNA结合特性，催化TRNA高加压酶
4. Investigation of migration behavior of rod-like dsDNA in gel with precisely controlled network structure [C] . Xiang Li, Kateryna Khairulina, Ung-il Chung, Symposium E "Fundamentals of Gels and Self-Assembly Systems" . 2014

机译：具有精确控制网络结构凝胶中棒状DSDNA的迁移行为的研究
5. Probing the mechanisms of the AlkB family DNA/RNA repair enzymes with a chemical cross-linking approach. [D] . Yi, Chengqi. 2010

机译：用化学交联方法探索AlkB家族DNA / RNA修复酶的机制。
6. Crystal structures of DNA/RNA repair enzymes AlkB and ABH2 bound to dsDNA [O] . Cai-Guang Yang, Chengqi Yi, Erica M. Duguid, -1

机译：与dsDNA结合的DNA / RNA修复酶AlkB和ABH2的晶体结构
7. Crystal Structure and RNA Binding Properties of the RNA Recognition Motif (RRM) and AlkB Domains in Human AlkB Homolog 8 (ABH8), an Enzyme Catalyzing tRNA Hypermodification* [O] . Chiara Pastore, Irini Topalidou, Farhad Forouhar, 2012

机译：RNA识别基序（RRM）和人ALKB同源物8（ABH8）中的RNA识别基序（RRM）和ALKB结构域的晶体结构和RNA结合特性，酶催化TRNA高加压*

Crystal structures of DNA/RNA repair enzymes AlkB and ABH2 bound to dsDNA

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