MAKING THE PAPER

摘要

For many years, proteins were given all the credit for mediating biochemical reactions in cells. That view changed in the early 1980s with the discovery that some RNA molecules that do not encode proteins can assume intricate three-dimensional forms and catalyse reactions. Since then, many RNA catalysts have been described, the most well-known being the ribosome - the cellular machinery for making proteins - the active complex of which consists of two large RNA molecules.