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Selective killing of cancer cells by a small molecule targeting the stress response to ROS

机译:通过靶向ROS应激反应的小分子选择性杀死癌细胞

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In this Letter we made errors in the description of the way we performed tumour measurements in the spontaneous (Fig. 2b and d) and the xenograft (Supplementary Fig. 9) mouse models. The legend of Fig. 2 incorrectly states that the graph of plotted tumour measurements represents tumour diameters from "grossly dissected tumours". Similarly, the Supplementary Fig. 9c legend incorrectly states that "After 3 weeks, tumour masses were excised and measured" and the legend of Supplementary Fig. 9d incorrectly states that: "After 3 weeks treatment, tumour sizes were measured". Instead, for the experiments in both Fig. 2 and Supplementary Fig. 9 we measured diameters of tumours in live mice at different time points (as indicated on the x axis of the graphs) during the course of the treatment. The tumours were measured between the skin surface layers using a caliper.
机译:在这封信中,我们在描述自发(图2b和d)和异种移植(补充图9)小鼠模型中进行肿瘤测量的方式时出现了错误。图2的图例错误地指出,绘制的肿瘤测量图表示“大体切开的肿瘤”的肿瘤直径。同样,补充图9c的图例错误地指出“ 3周后,切除并测量了肿瘤块”,而补充图9d的图例错误地指出:“治疗3周后,测量了肿瘤的大小”。相反,对于图2和补充图9中的实验,我们在治疗过程中的不同时间点(如图X轴所示)测量了活小鼠的肿瘤直径。使用卡尺在皮肤表面层之间测量肿瘤。

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