Order from disorder sprung

摘要

During the past few years, the advent of hugely powerful DNA-sequencing technologies has delivered unprecedented insight into the nature of cancer genomes. Hundreds of examples of genomes from several cancer types have already been produced, and this process will continue so that a definitive overview of cancer genomics can eventually be achieved. Nevertheless, it seems apposite to take stock of the themes that are emerging from comparisons of the genomes of different tumour types - studies that are giving us a fascinating first peek at the common mutational events and processes that shape cancer genomes.