Exploring new treatment opportunities in ischaemic stroke: Lundbeck's perspective and current research

摘要

Stroke is a medical emergency that results from a sudden disruption in blood flow to the brain, caused either by obstruction of an artery (ischaemic stroke) or bleeding from an intracranial blood vessel (haemorrhagic stroke). Stroke manifests itself clinically through various neurological deficits (motor, sensory or complex functional deficits) determined by where in the brain the lesion is localized. Patients may exhibit the same symptoms irrespective of the type of stroke. Population-based studies in many countries have shown that 80-85% of all stroke events are ischaemic, also called acute ischaemic stroke (AIS). Lundbeck is developing the agent desmoteplase for the treatment of AIS; this paper describes research on desmoteplase and provides Lundbeck's perspective on current developments in AIS treatment.