Northwestern University researchers develop a new method to deliver molecules into targeted cells

摘要

Researchers at Northwestern Universityn(IL, USA) have developed a new method,nnamed nanofountain-probe electroporationn(NFP-E), which allows the deliverynof molecules into targeted cells throughntemporary nanopores in the cell membranencreated by a localized electric field appliednto a small portion of the cell. In the study,nthe scientists demonstrated NFP-E of singlenHeLa cells within a population, deliveringnmolecules to a target cell with over 95% transfection efficiency, qualitativendosage control and high viability (92%)nof transfected cells.