NCI-Sponsored Trial for the Evaluation of Safety and Preliminary Efficacy of 3′-Deoxy-3′-[18F]fluorothymidine (FLT) as a Marker of Proliferation in Patients with Recurrent Gliomas: Preliminary Efficacy Studies

Alexander M. Spence; Mark Muzi; Jeanne M. Link; Finbarr O’Sullivan; Janet F. Eary; John M. Hoffman; Lalitha K. Shankar; Kenneth A. Krohn

首页> 外文期刊>Molecular Imaging and Biology >NCI-Sponsored Trial for the Evaluation of Safety and Preliminary Efficacy of 3′-Deoxy-3′-[18F]fluorothymidine (FLT) as a Marker of Proliferation in Patients with Recurrent Gliomas: Preliminary Efficacy Studies

【24h】

NCI-Sponsored Trial for the Evaluation of Safety and Preliminary Efficacy of 3′-Deoxy-3′-[18F]fluorothymidine (FLT) as a Marker of Proliferation in Patients with Recurrent Gliomas: Preliminary Efficacy Studies

机译：NCI赞助的评估3'-脱氧-3'-[18 F]氟胸苷（FLT）作为复发性胶质瘤患者增殖指标的安全性和初步疗效的初步疗效研究

获取原文

获取原文并翻译 | 示例

获取外文期刊封面封底 >>

开具论文收录证明 >>

文献代查 >>

页面导航

摘要
著录项
相似文献
相关主题

摘要

3′-Deoxy-3′-[18F]fluorothymidine ([18F]FLT) is being developed for imaging cellular proliferation. The goals were to explore the capacity of FLT-positron emission tomography (PET) to distinguish between recurrence and radionecrosis in gliomas and compare the results to those obtained with 2-fluoro-2-deoxy-d-glucose (FDG).

机译：3'-Deoxy-3'-[18 F]氟胸苷（[18 F] FLT）正在开发中，用于细胞增殖成像。目的是探索FLT正电子发射断层扫描（PET）的能力，以区分神经胶质瘤的复发和放射性坏死，并将结果与使用2-氟-2-脱氧-d-葡萄糖（FDG）获得的结果进行比较。

著录项

来源
《Molecular Imaging and Biology》 |2009年第5期|343-355|共13页
作者
Alexander M. Spence; Mark Muzi; Jeanne M. Link; Finbarr O’Sullivan; Janet F. Eary; John M. Hoffman; Lalitha K. Shankar; Kenneth A. Krohn;
展开▼
作者单位

Department of Neurology University of Washington Mailstop 356465 1959 NE Pacific Street Seattle WA 98195 USA;

Department of Radiology University of Washington Seattle WA USA;

Department of Radiology University of Washington Seattle WA USA;

Department of Statistics University College Cork Cork Ireland;

Department of Radiology University of Washington Seattle WA USA;

Departments of Radiology and Neurology University of Utah Salt Lake City UT USA;

Cancer Imaging Program Division of Cancer Treatment and Diagnosis National Cancer Institute Bethesda MD USA;

Department of Radiology University of Washington Seattle WA USA;

展开▼
收录信息
原文格式 PDF
正文语种 eng
中图分类
关键词
3′-18Ffluoro-3′-deoxythymidine; FLT; Fluorothymidine; Positron emission tomography (PET); Glioma; Radionecrosis; Proliferation imaging;

机译：3′-[18F]氟-3′-脱氧胸苷;FLT;氟胸苷;正电子发射断层显像（PET）;神经胶质瘤;放射性坏死;增殖成像;

相似文献

外文文献
中文文献

1. NCI-sponsored trial for the evaluation of safety and preliminary efficacy of 3'-deoxy-3'-(18F)fluorothymidine (FLT) as a marker of proliferation in patients with recurrent gliomas: preliminary efficacy studies. [J] . Spence AM, Muzi M, Link JM Molecular imaging and biology: MIB : the official publication of the Academy of Molecular Imaging . 2009,第5期

机译：由NCI发起的评估3'-脱氧-3'-（18F）氟胸苷（FLT）作为复发性神经胶质瘤患者增殖指标的安全性和初步疗效的试验：初步疗效研究。
2. NCI-Sponsored Trial for the Evaluation of Safety and Preliminary Efficacy of FLT as a Marker of Proliferation in Patients with Recurrent Gliomas: Safety Studies [J] . Alexander M. Spence, Mark Muzi, Jeanne M. Link, Molecular Imaging and Biology . 2008,第5期

机译：NCI赞助的用于评估FLT作为复发性胶质瘤患者增殖指标的安全性和初步疗效的试验：安全性研究
3. NCI-sponsored trial for the evaluation of safety and preliminary efficacy of FLT as a marker of proliferation in patients with recurrent gliomas: safety studies. [J] . Spence AM, Muzi M, Link JM, Molecular imaging and biology: MIB : the official publication of the Academy of Molecular Imaging . 2008,第5期

机译：由NCI发起的用于评估FLT作为复发性神经胶质瘤患者增殖指标的安全性和初步疗效的试验：安全性研究。
4. Inununohistochemical and Molecular Markers of Proliferation and Apoptosis in Stereotactic Bioptates of Brain Gliomas Prognosis of the Course of the Disease and the Treatment Efficacy [C] . G. Bierzynska-Macyszyn, U. Mazurek, P. Wlaszczuk, World Society for Stereotactic and Functional Neurosurgery . 2005

机译：疾病过程脑胶质瘤脑胶质瘤脑胶质术后凋亡和细胞凋亡的肝细胞化学和分子标记及治疗疗效
5. Preliminary safety and biological efficacy studies of ethyl pyruvate in normal adult horses [D] . Schroeder, Eric Lee 2011

机译：丙酮酸乙酯在正常成年马中的初步安全性和生物学功效研究
6. NCI-Sponsored Trial for the Evaluation of Safety and Preliminary Efficacy of 3′-Deoxy-3′-18F fluorothymidine (FLT) as a Marker of Proliferation in Patients with Recurrent Gliomas: Preliminary Efficacy Studies [O] . Alexander M. Spence, Mark Muzi, Jeanne M. Link, -1

机译：NCI赞助试验用于评估3-DEOXY-3 - 18F氟脲酰胺（FLT）作为复发性胶质瘤患者的增殖标志物：初步疗效研究
7. C2-07: A phase III clinical trial to evaluate the measurement of tumor proliferation using 18FFluoro-3' deoxy-3'-L-fluorothymidine (FLT) positron emission tomography in patients with lung cancer [O] . Ryu Jin-Sook, Oh Seung Jun, Im Ki-Chun, 2007

机译：C2-07：一项III期临床试验，评估使用18F Fluoro-3'脱氧-3'-L-氟胸苷（FLT）正电子发射断层扫描术对肺癌患者的肿瘤增殖测量

NCI-Sponsored Trial for the Evaluation of Safety and Preliminary Efficacy of 3′-Deoxy-3′-[18F]fluorothymidine (FLT) as a Marker of Proliferation in Patients with Recurrent Gliomas: Preliminary Efficacy Studies

摘要

著录项

相似文献

相关主题

期刊订阅