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首页> 外文期刊>Journal of Toxicology and Environmental Health, Part A: Current Issues >Probabilistic Human Health Risk Assessment for Quarterly Exposure to High Chloroform Concentrations in Drinking-Water Distribution Network of the Province of Quebec, Canada
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Probabilistic Human Health Risk Assessment for Quarterly Exposure to High Chloroform Concentrations in Drinking-Water Distribution Network of the Province of Quebec, Canada

机译:加拿大魁北克省饮用水分配网络中每季度高氯仿浓度暴露的概率人类健康风险评估

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摘要

Because quarterly concentrations of total trihalomethanes (THM) exceeding the 80 μg/L guideline are often tolerated by the public health authorities of the Province of Quebec (Canada), this study examined whether quarterly episodes of high concentrations of THM may pose a risk to the health of its population. Using Monte Carlo simulations, a probabilistic risk assessment was performed for infants (0-<6 mo), toddlers (6 mo-80 μg/L), the 95th percentile value of RQ were 0.65, 0.46, and 0.24 for infants, toddlers, and adults, respectively. Back-calculation allowed determining that a chloroform concentration of 330 μg/L would result in RQ ≤ 1 for 99% of infants, the subgroup considered the most susceptible among the general population. Overall, this study showed that episodes of high THM concentration encountered in Quebec drinking-water distribution network need not be considered as an immediate health concern for the general population. However, these results should not be interpreted as an authorization to exceed the 80 μg/L standard but rather as a risk management tool for public health authorities.
机译:由于魁北克省(加拿大)的公共卫生部门经常容忍季度总三卤甲烷(THM)浓度超过80μg/ L的季度浓度,因此,本研究检查了季度高浓度THM的发作是否可能对其人口的健康状况。使用蒙特卡洛模拟,对婴儿(0- <6 mo),幼儿(6 mo-80μg/ L),概率95的RQ值分别进行了概率风险评估,婴儿,幼儿为0.65、0.46和0.24,和成年人。反向计算允许确定330μg/ L的氯仿浓度将导致99%的婴儿RQ≥1,该亚组被认为是一般人群中最易感的。总体而言,这项研究表明,在魁北克饮用水分配网络中遇到的高THM浓度事件不必被视为普通民众的直接健康问题。但是,这些结果不应解释为超过80μg/ L标准的授权,而应视为公共卫生当局的风险管理工具。

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