Pseudospecificity of the Acidic Patch of Plastocyanin for the Interaction with Cytochrome f

摘要

The interaction between electron transfer (ET) proteins is usually transient in nature, which is essential for physiological function. The specificity of such reactions is maintained without compromising the need for a rapid flow of electrons. Long-range electrostatic forces enhance association and preorient the partners, whereas hydrophobic interactions (which are effective over shorter distances) are important for reactive encounter complex formation.