Cp_2TiCI_2-Catalyzed Regio-and Chemoselective One-Step Synthesis of gamma-Substituted Allylsilanes from Terminal Alkenes Using Dianion-Type Zincate (SiSiNOL-Zn-ate)

摘要

Allylsilanes are important intermediates for carbon-carbon and carbon-heteroatom bond formation in organic synthesis because of their easy handling,unique reactivities,and high regiocontrol-lability.Methods currently available for their synthesis include transition-metal-catalyzed silylmetalation of 1,3-dienes or allenes and Wittig reactions.Unfortunately,however,many of these reactions have significant disadvantages:low generality,low chemoselectivity,the requirement for tedious multistep synthesis of the precursor,and so on.