Activity Increase of Horseradish Peroxidase in the Presence of Magnetic Particles

摘要

Magnetic field effects (MFE) on enzymatic reactions have been investigated as early as the 1960s, and most of the experiments carried out initially reported no effect on the reaction rates. In the mid-1980s focus was turned to radical pairs; in the context of the radical pair recombination theory, the effect of magnetic fields on biological reactions with paramagnetic species was studied. Recently, a number of publications examined the effect of an external magnetic field and that of spin orbit coupling (SOC) on the kinetics of enzymatic reactions. In particular, evidence was found for the existence of a magnetosensitive step in the catalytic cycle of horseradish peroxidase (HRP).