Nanoengineered Electrically Contacted Enzymes on DNA Scaffolds: Functional Assemblies for the Selective Analysis of Hg~(2+) Ions

摘要

The electrical contacting of redox enzymes with electrodes is one of the most fundamental processes required for the development of bioelectronic devices, such as amperometric biosensors or biofuel cells. Recently, DNA monolayers assembled on electrodes were shown to act as templates for the organization of relay (cofactor) and enzyme units, leading to the controlled electrical contacting of the enzymes with the electrode.