Metal-Free Oxidative Trifluoromethylthiolation of Terminal Alkynes with CF_3SiMe_3 and Elemental Sulfur

摘要

A metal-free oxidative trifluoromethyl-thiol-ation of terminal alkynes using readily available CF_3SiMe_3 and elemental sulfur at room temperature has been developed. This reaction provides an efficient and convenient method for the preparation of alkynyl trifluoromethyl sulfides bearing a wide range of functional groups. Preliminary investigation revealed that elemental sulfur instead of air acted as the oxidant.