A method based on mutual information and gradient information for medical image registration

摘要

Mutual information is widely used in medical image registration, because it does not require preprocessing the image. However, the local maximum problem in the registration is insurmountable. We combine mutual information and gradient information to solve this problem and apply it to the non-rigid deformation image registration. To improve the accuracy, we provide some implemental issues, for example, the Powell searching algorithm, gray interpolation and consideration of outlier points. The experimental results show the accuracy of the method and the feasibility in non-rigid medical image registration.