Acidic, Selective Monoacylation of vic-Diols

摘要

Selective transformation of diols is an important subject in synthetic chemistry. Several methods have been developed for monoderivatization of polyols, e.g., by means of dibutylstannylene acetals or monoalkoxide sodium salt, nucleophilic opening of benzylidene-type acetals, and transderivatization catalyzed by metallic sulfates or ion-exchange resins. Herein we report an effective method for monoacylation of vic-diols under acidic conditions.