Copper-Catalyzed Electrophilic Animation of Functionalized Diarylzinc Reagents

摘要

The copper-catalyzed electrophilic amination of functionalized diarylzinc reagents with O-acyl hydroxylamines allows for the preparation of functionalized tertiary arylamines in high yields,and is noteworthy for the mild reaction conditions employed.The functionalized diarylzinc reagents were prepared via an iodine/magnesium exchange of the corresponding aryl iodide followed by transmetalation of the resultant Grignard species with ZnCl_2.