Synthesis of Chinensines A—E

摘要

Short and efficient syntheses of coronarin E (4) and chinensines A—E (5—9) have been accomplished. The use of two different types of reaction of singlet oxygen (~1O_2) lies at the heart of the synthetic strategy. The syntheses have facilitated the clarification of certain previously unknown, or unconfirmed, stereochemical details (the relativity stereochemistries of chinensines D and E and the absolute stereochemistries for all the synthesized family members).