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首页> 外文期刊>Journal of economic theory >How (not) to integrate blood subtyping technology to kidney exchange
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How (not) to integrate blood subtyping technology to kidney exchange

机译:如何(不)将血液分型技术整合到肾脏交换中

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Even though kidney exchange became an important source of kidney transplants over the last decade with the introduction of market design techniques to organ transplantation, the shortage of kidneys for transplantation is greater than ever. Due to biological disadvantages, patient populations of blood types B/O are disproportionately hurt by this increasing shortage. The disadvantaged blood types are overrepresented among minorities in the US. In order to mitigate the disproportionate harm to these biologically disadvantaged groups, the UNOS reformed in 2014 the US deceased-donor kidney-allocation system, utilizing a technological advance in blood typing. The improved technology allows a certain fraction of blood type A kidneys, referred to as subtype A2 kidneys, to be transplanted to medically qualified patients of blood types B/O. The recent reform prioritizes subtype A2 deceased-donor kidneys for blood type B patients only. When restricted to the deceased-donor allocation system, this is merely a distributional reform with no adverse impact on the overall welfare of the patient population. In this paper we show that the current implementation of the reform has an unintended consequence, and it de facto extends the preferential allocation to kidney exchange as well. Ironically this "spillover" not only reduces the number of living-donor transplants for the overall patient population, but also for the biologically disadvantaged groups who are the intended beneficiaries of the reform. We show that minor variations of the current policy do not suffer from this unintended consequence, and we make two easy-to-implement, welfare-increasing policy recommendations. (C) 2018 Elsevier Inc. All rights reserved.
机译:尽管在过去的十年中,随着器官移植市场设计技术的引入,肾脏置换已成为肾脏移植的重要来源,但肾脏移植的短缺比以往任何时候都更加严重。由于生物学上的不利因素,这种不断增加的短缺严重地损害了B / O型血的患者群体。在美国的少数族裔中,弱势人群的血型过多。为了减轻对这些生物弱势群体的不成比例的伤害,UNOS于2014年利用血液分类技术的先进性,对美国死者肾脏分配系统进行了改革。改进的技术允许将一定比例的A型血液肾脏(称为A2亚型肾脏)移植到医学上合格的B / O型患者。最近的改革仅将B2型血液患者的A2型亚型供体肾优先。当仅限于死者捐赠者分配系统时,这仅仅是分配改革,不会对患者群体的整体福利产生不利影响。在本文中,我们表明,当前的改革实施具有意想不到的后果,并且事实上也将优惠分配扩展到了肾脏交换。具有讽刺意味的是,这种“溢出”不仅减少了整个患者群体的活体供体移植数量,而且减少了作为改革受益者的生物弱势群体。我们表明,当前政策的细微变化不会受到这种意想不到的后果的困扰,并且我们提出了两个易于实施,增加福利的政策建议。 (C)2018 Elsevier Inc.保留所有权利。

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