Abnormal spiral artery remodelling in the decidual segment during pregnancy: from histology to clinical correlation

摘要

Introduction Modification of the spiral arteries with loss of the muscular vascular wall, invaded by the trophoblasts, represents the goal of the physiological vascular adaptation during human implantation. When physiological vascular changes do not occur, an unfavourable evolution of gestation may develop as suggested by uterine biopsies studies.