Tomato Lycopene May Affect The Igf-system

摘要

Results of a study published in the November 2007 American Journal of Clinical Nutrition suggest that supplementing the diet with tomato lycopene may interfere with the insulin-like growth factor (IGF) system and thereby possibly decrease cancer risk.rnThe eight week double-blind study, funded by the Dutch Cancer Society, investigated the effect of supplementation with 30 mg/day of tomato lycopene on serum concentrations of IGF-I and -II which are associated with increased prostate, premenopausal breast, and colorectal cancer risk, and on their binding proteins (IGFBP-1, -2, and -3). Seventy-six men and women at greater risk ofrncolorectal cancer participated in this trial using tomato lycopene capsules supplied by LycoRed Ltd., Israel.