Drug release from matrix systems: analysis by finite element methods

摘要

In this work some problems in drag delivery from solid systems were described in terms of transient mass balances with diffusion and solved by using FEM. Firstly, the solving codes were compared with known analytical solutions, available for simple problems (simple geometries, constant diffusivities). Then, models were written to describe more realistic systems (complex geometries, variable diffusivities). Eventually, the behaviors of some real drug delivery systems were successfully predicted.