Effects of acute coronary occlusion and previous ischaemic injury on left ventricular wall motion in humans

摘要

Conclusions-In stable angina intra- coronary balloon inflation aggravated pre-existing systolic and diastolic abnor- malities in the territory of the occluded vessel, indicating the dependence of both on coronary flow. In unstable angina bal- loon inflation caused only minor deterio- ration in systolic function, and diastolic changes-including the characteristic abnormal shortening during isovolumic relaxation-were unaffected. Thus resting abnormalities of left ventricular function in unstable angina are effectively dissoci- ated from acute changes in coronary flow.