Ischaemic preconditioning reduces troponin T release in patients undergoing coronary artery bypass surgery

摘要

Conclusions-The direct application of a preconditioning stimulus in clinical prac- tice has been shown, for the first time, to protect patients against irreversible myocyte injury. Objective-To investigate whether ischae- Mic preconditioning could reduce myo- Cardial injury, as manifest by troponin T Release, in patients undergoing elective Coronary artery bypass surgery. Design-Randomised controlled trial. Setting-Cardiothoracic unit of a tertiary Care centre. Patients-Patients with three vessel coro- Nary artery disease and stable angina Admitted for first time elective coronary Artery bypass surgery were invited to take Part in the study; 33 patients were ran- Domised into control or preconditioning Groups.