Microwave assisted extraction of phenolic compounds from four economic brown macroalgae species and evaluation of their antioxidant activities anc inhibitory effects on a-amylase, α-glucosidase, pancreatic lipase and tyrosinase

摘要

Four economically important brown algae species (Ascophyllum nodostun, Laminaria japonica, Lessonia trabeculate and Lessonia nigrecens) were investigated for phenolic compound extraction and evaluated for their antioxidant, anti-hyperglycemic, and pancreatic lipase and tyrosinase inhibition activities. Microwave assisted extraction (MAE) at 110 degrees C for 15 min resulted in both higher crude yield and higher total phenolic content (TPC) for all algae species compared with those obtained by conventional extraction at room temperature for 4 h, and Ascophyllum nodoswn yielded the highest TPC. Antioxidant tests indicated that extracts acquired by MAE from four species all exhibited higher DPPH, ABTS free radical scavenging ability and reducing power than the conventional method. The extract of Lessonia trabeculate exhibited good a-amylase, a-glucosidase, pancreatic lipase, and tyrosinase inhibition activities, and the MAE extract showed even better a-glucosidase inhibitory activity than acarbose.