The applicability of the ADI (Acceptalbe Daily Intake) for food additives to infants and children

摘要

Children are not little adults. Children may respond differently from adults because they are in a state of growth and development; of because of differences in toxicokinetics or toxicodynamics. Infants and children are often assumed to be more susceptible to toxic effects, but this generalization is founded on assump- tions rather than on facts. Available data are mostly concerned with toxicity ad therapeutic effects of pharmaceuticals, while the effects in children of in- dustrial chemicals are less well documented.