Age Differences in Immunohistochemical Localizations of Large Proteoglycan, PG-M/versican, and Small Proteoglycan, Decorin, in the Dermis of Rats

摘要

Proteoglycans were localized immunohistochemically in the dermis of Donryu rats, using monoclonal antibodies raised against large protegolycan(PG-M/versican)and small proteoglycan(decorin). The localization of these proteglycans in the dermis were compared between young rats(22-days old)and old ones(24 or 30 months of age), and distinct age differences were observed.