The Effects of Medetomidine on Maternal and Fetal Cardiovascular and Pulmonary Function, Intrauterine Pressure and Uterine Blood Flow in Pregnant Goats

摘要

To investigate the effects of medetomidine on late pregnant goats, medetomidine induced changes in maternal or fetal circulation and acid-base balance, as well as changes in intrauterine pressure (IUP) and uterine blood flow (UFB), were studied. Intramuscular administration of medetomidine (40 μg/kg b.w.) decreased the heart rate (HR) and arterial blood pressure (ABP) of the mother, and the change in HR was significant statistically (p＜0.05). In the fetus, HR and ABP showed transient decrease and increase (p＜0.05), respectively.