Contamination of Mouse-adapted Influenza Virus with Sendai Virus

摘要

In our laboratory animal facility, Sendai virus (HVJ) contamination occurred in a negative flow rack use for experimental infection with 4 strains of mouse-adapted influenza virus (Inf.V). Anti-HVJ antibody (Ab) was detected in 35/42 mice in the rack. To specify the strain of Inf. V contaminated with HVJ, experimental infection was performed by using A, B and D strains of Inf. V in each vinly isolator. Anti-HVJ Ab was detected in all mice infected with A strain at day 28 post-infection.