Biochemical and behavioral effects of carbofuran in goldfish (Carassius auratus)

摘要

The effects of concentration(5, 50, and 500 μg/L) and duration(24, 48 h) of exposure to carbofuran, a carbamate insecticide, were assessed on brain catecholamine(norepinephrine[NE] and dopamine), plasma glucose, and hepatic glycogen contents and behavioral activities of goldfish(Carassius auratus). After 24 h of exposure to 50 and 500 μg/L, the level of NE was increased in the olfactory bulbs. The same effect was observed after a 48-h exposure to 500 μg/L in the telencephalic hemispheres and in the hypothalamus, respectively. An increase in the level of dopamine was also found in hypothalamus after 48 h of exposure to 500μ μg/L carbofuran.