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Comparative researches on effects of sodium dodecylbenzene sulfonate and sodium dodecyl sulfate upon Lateolabrax japonicus biomarker system

机译:十二烷基苯磺酸钠和十二烷基硫酸钠对日本乳草生物标记体系影响的比较研究

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摘要

Fish Lateolabrax japonicus were exposed to anion surfactant sodium dodecylbenzene sulfonate (SDBS) and sodium dodecyl sulfate (SDS) at 1 mg/l, respectively, for 6, 12 and 18 d, with one control group. Liver antioxidant enzymes, including superoxide dismutase (SOD), catalase (CAT), glutathione peroxidase (GPx), reduced glutathione (GSH) and glutathione S-transferase (GST) were determined; brain acetylcholinesterase (AChE) and liver inducible nitric oxide synthase (iNOS) activities were also measured. The results of the study indicated that these parameters made different, sometimes, adverse responses to SDBS and SDS exposure, such as the activity of iNOS can be inhibited by SDBS and induced by SDS, the different physico-chemical characteristics of SDBS and SDS should be responsible for their effects on enzyme activities.
机译:一个对照组将分别以1 mg / l的浓度将阴离子型鱼类表面活性剂十二烷基苯磺酸钠(SDBS)和十二烷基硫酸钠(SDS)暴露于鱼类Lateolabrax japonicus,分别放置6、12和18 d。测定了肝脏抗氧化酶,包括超氧化物歧化酶(SOD),过氧化氢酶(CAT),谷胱甘肽过氧化物酶(GPx),还原型谷胱甘肽(GSH)和谷胱甘肽S-转移酶(GST)。还测量了脑乙酰胆碱酯酶(AChE)和肝诱导型一氧化氮合酶(iNOS)的活性。研究结果表明,这些参数有不同之处,有时对SDBS和SDS的暴露有不良反应,例如iNOS的活性可以被SDBS抑制并被SDS诱导,SDBS和SDS的理化特性应不同。它们对酶活性的影响。

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