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Evaluation of a Novel Approach for Reducing Emissions of Pharmaceuticals to the Environment

机译:减少药物向环境排放的新方法的评估

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摘要

Increased interest over the levels of pharma-ceuticals detected in the environment has led to the need for new approaches to manage their emissions. Inappropriate disposal of unused and waste medicines and release from manufacturing plants are believed to be important pathways for Pharmaceuticals entering the environment. In situ treatment technologies, which can be used on-site in pharmacies, hospitals, clinics, and at manufacturing plants, might provide a solution. In this study we explored the use of Pyropure, a microscale combined pyrolysis and gasification in situ treatment system for destroying pharmaceutical wastes. This involved selecting 17 Pharmaceuticals, including 14 of the most thermally stable compounds currently in use and three of high environmental concern to determine the technology's success in waste destruction. Treatment simulation studies were done on three different waste types and liquid, solid, and gaseous emissions from the process were analyzed for parent pharmaceutical and known active transformation products. Gaseous emissions were also analyzed for NOx, particulates, dioxins, furans, and metals. Results suggest that Pyropure is an effective treatment process for pharmaceutical wastes: over 99 % of each study pharmaceutical was destroyed by the system without known active transformation products being formed during the treatment process. Emissions of the other gaseous air pollutants were within acceptable levels. Future uptake of the system, or similar in situ treatment approaches, by clinics, pharmacists, and manufacturers could help to reduce the levels of pharmaceuticals in the environment and reduce the economic and environmental costs of current waste management practices.
机译:人们对在环境中检测到的药物的关注程度越来越高,这导致需要新的方法来控制其排放。人们认为,不适当处置未使用的和废弃的药物以及从生产工厂中释放出来是药物进入环境的重要途径。可以在药房,医院,诊所和制造工厂现场使用的原位处理技术可能会提供解决方案。在这项研究中,我们探索了Pyropure(一种微型热解和气化原位联合处理系统)用于消灭制药废物的用途。这涉及选择17种药品,包括14种目前正在使用的最热稳定的化合物和3种对环境的高度关注,以确定该技术在废物破坏方面的成功。对三种不同的废物类型进行了处理模拟研究,并对过程中的液体,固体和气体排放进行了分析,以寻找母体药物和已知的活性转化产物。还分析了气体排放物中的氮氧化物,微粒,二恶英,呋喃和金属。结果表明,Pyropure是一种有效的药物废物处理方法:每种研究药物的99%以上都被系统破坏,而在处理过程中没有形成已知的活性转化产物。其他气态空气污染物的排放在可接受的水平之内。诊所,药剂师和制造商将来会采用该系统或类似的原位处理方法,这可能有助于降低环境中的药物含量,并降低当前废物管理实践的经济和环境成本。

著录项

  • 来源
    《Environmental Management》 |2016年第4期|707-720|共14页
  • 作者单位

    Environment Department, University of York, York YO10 5DD, UK,Department of Environmental Science and Technology, University of Maryland, Maryland, MD 20742, USA;

    Centre of Excellence in Mass Spectrometry and Department of Chemistry, University of York, York YO10 5DD, UK;

    Centre of Excellence in Mass Spectrometry and Department of Chemistry, University of York, York YO10 5DD, UK;

    PyroPure Ltd, Unit 58 Woolmer Trading Estate, Bordon, Hampshire GU35 9QF, UK;

    PyroPure Ltd, Unit 58 Woolmer Trading Estate, Bordon, Hampshire GU35 9QF, UK;

    PyroPure Ltd, Unit 58 Woolmer Trading Estate, Bordon, Hampshire GU35 9QF, UK;

    Environment Department, University of York, York YO10 5DD, UK;

  • 收录信息 美国《科学引文索引》(SCI);美国《工程索引》(EI);美国《化学文摘》(CA);
  • 原文格式 PDF
  • 正文语种 eng
  • 中图分类
  • 关键词

    Pharmaceutical waste; Thermal decomposition; Pyrolysis-gasification; Stewardship; Take-back strategy; Antimicrobial resistance;

    机译:制药废物;热分解;热解气化;管家;收回策略;抗菌素耐药性;

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