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Population-based mortality data suggests remediation is modestly effective in two Montana Superfund counties

机译:基于人口的死亡率数据表明修复在两名蒙大拿州超级县谦虚有效

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The health effects of living in proximity to Superfund sites with ongoing remediation were evaluated for residents of two contiguous Montana counties, Deer Lodge and Silver Bow. Deer Lodge and Silver Bow are home to the Anaconda Smelter and Silver Bow Creek/Butte Area Superfund sites, respectively. Established by the Environmental Protection Agency in 1983, both sites have had ongoing remediation for decades. Employing county level death certificate data obtained from the Centers for Disease Control and Prevention WONDER site, sex and age-adjusted standardized mortality ratios (SMRs) for composite targeted causes of death were calculated using observed versus expected mortality for both counties, and compared to the expected mortality from the remaining Montana counties. Cancers, cerebro- and cardiovascular diseases (CCVD), and organ failure were elevated for the two counties during the study period, 2000-2016, with SMRs of 1.19 (95% CI 1.10, 1.29); 1.36 (95% CI 1.29, 1.43); and 1.24 (95% CI 1.10, 1.38), respectively. Neurological conditions were not elevated for the two counties (SMR=1.01; 95% CI 0.89, 1.14). Time trend analyses performed using Cox regression models indicate that deaths from cancers (HR=0.97; p=0.0004), CCVDs (HR=0.95; p0.0001), and neurological conditions (HR=0.97; p=0.01) decreased over the study period. While the ecological approach applied limits the interpretation of our results, our study suggests that while mortality is elevated, it is also decreasing over time for these two Superfund sites.
机译:为两种连续蒙大拿县,鹿小屋和银弓的居民评估了在持续的修复附近生活在持续修复附近的健康影响。鹿旅馆和银弓分别是蟒蛇冶炼厂和银弓溪/小屋超级朋格的所在地。 1983年由环境保护局建立,这两个网站已经持续了几十年的修复。雇用县级死亡证明书从疾病控制和预防奇迹网站,性别和年龄调整的标准化死亡率(SMR)获得的复合目标死因的核心目标死亡的核心病例,使用观察到的与县的预期死亡率进行计算,并与剩下的蒙大拿县的预期死亡率。 2000 - 2016年研究期间的两次癌症,脑和心血管疾病(CC​​VD)和器官衰竭升高,SMR为1.19(95%CI 1.10,1.29); 1.36(95%CI 1.29,1.43);分别为1.24(95%CI 1.10,1.38)。神经病学条件未升高两县(SMR = 1.01; 95%CI 0.89,1.14)。使用COX回归模型进行的时间趋势分析表明来自癌症的死亡(HR = 0.97; p = 0.0004),CCVDS(HR = 0.95; p0.0001)和神经系统条件(HR = 0.97; P = 0.01)减少时期。虽然生态方法应用限制了我们的结果解释,但我们的研究表明,虽然死亡率升高,但这两个超级朋格的时间随着时间的推移也会降低。

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