Acute electroretinographic changes during Sildenafil (Viagra) treatment for erectile dysfunction*

摘要

The authors describe their findings on 12 subjects who were treated with 50 mg of Sildenafil (Viagra) and underwent ERG measurements prior to and 1 hour after ingestion. The Naka–Rushton equation was used to describe the b-wave luminance-response function of the scotopic ERG. Statistically significant differences were noted in the V max and K values. Sildenafil ingestion resulted in an increase in V max (higher rod response to light stimuli) and a decrease in K (higher sensitivity).