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首页> 外文期刊>Diabetes >Vasoactive Intestinal Peptide-Null Mice Demonstrate Enhanced Sweet Taste Preference, Dysglycemia, and Reduced Taste Bud Leptin Receptor Expression
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Vasoactive Intestinal Peptide-Null Mice Demonstrate Enhanced Sweet Taste Preference, Dysglycemia, and Reduced Taste Bud Leptin Receptor Expression

机译：血管活性肠肽无效小鼠表现出增强的甜味偏好，血糖异常和味蕾芽瘦素受体表达降低

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摘要

It is becoming apparent that there is a strong link between taste perception and energy homeostasis. Recent evidence implicates gut-related hormones in taste perception, including glucagon-like peptide 1 and vasoactive intestinal peptide (VIP). We used VIP knockout mice to investigate VIP's specific role in taste perception and connection to energy regulation.
机译：越来越明显的是，味觉与能量稳态之间存在着紧密的联系。最近的证据表明，与肠相关的激素与味觉有关，包括胰高血糖素样肽1和血管活性肠肽（VIP）。我们使用VIP敲除小鼠研究了VIP在味觉感知和与能量调节相关中的特定作用。

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  • 来源
    《Diabetes》 |2010年第5期|p.1143-1152|共10页
  • 作者

    Bronwen Martin Yu-Kyong Shin Caitlin M White Sunggoan Ji Wook Kim Olga D Carlson Joshua K Napora Wayne Chadwick Megan Chapter James A Waschek Mark P Mattson Stuart Maudsley Josephine M Egan;

  • 作者单位

    Bronwen Martin,1 Yu-Kyong Shin,1 Caitlin M. White,1 Sunggoan Ji,1 Wook Kim,1 Olga D. Carlson,1 Joshua K. Napora,1 Wayne Chadwick,1 Megan Chapter,1 James A. Waschek,2 Mark P. Mattson,1 Stuart Maudsley,1 and Josephine M. Egan1From the 'National Institutes of Health. National Institute on Aging. Baltimore. Maryland, and the "Department of Psychiatry and Behavioral Sciences, Mental Retardation Research Center, Semel Institute for Neuroscience and Human Behavior. University of California. Los Angeles. Los Angeles. California.Corresponding author: Josephine Egan, eganj@mail.iuli.gov.Received 10 June 2009 and accepted 28 January 2010. Published ahead of print at http://diabetes.diabetesjournals.org on 11 February 2010. DOI: 10.2337/db09-0807.B. M. and Y. -K.S. contributed equally to this study.© 2010 by the American Diabetes Association. Readers may use this article as long as the work is properly cited, the use is educational and not for profit. and the work is not altered. See http://creativeconmions.org/licenses/by -nc-nd/3.0/ for details.The costs of publication of this article were defrayed in purl by /he payment of paye charges. This unirle musi therefore be hereby marked "advertisement" in accordance ieilh IS U.S.C. Section 1734 solely to indicate this fact.,;

  • 收录信息 美国《科学引文索引》(SCI);美国《化学文摘》(CA);
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