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Short-Term Administrations of a Combination of Anti-LFA-1 and Anti-CD154 Monoclonal Antibodies Induce Tolerance to Neonatal Porcine Islet Xenografts in Mice

机译:短期施用抗-LFA-1和抗CD154单克隆抗体的组合可诱导小鼠新生猪胰岛异种移植的耐受性。

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摘要

The objective of this study was to determine whether tolerance to neonatal porcine islet (NPI) xenografts could be achieved by short-term administrations of anti-LFA-1 and anti-CD154 monoclonal antibodies (mAbs).
机译:这项研究的目的是确定是否可以通过短期施用抗-LFA-1和抗-CD154单克隆抗体(mAb)来实现对新生猪胰岛(NPI)异种移植的耐受性。

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  • 来源
    《Diabetes》 |2010年第4期|p.958-966|共9页
  • 作者单位

    Hossein Arefanian,1,2 Eric B. Tredget,1 Ray V. Rajotte,1 Ron G. Gill,3 Gregory S. Korbutt,1 and Gina R. Rayat1From the 'Alberta Diabetes Institute. Department of Surgery, University of Alberta, Edmonton, Alberta, Canada: the -Endocrinology and Metabolism Research Center. Dr. Shariati Hospital, Tehran University of Medical Sciences, North Kargar Avenue, Tehran, Iran, and the 3 Alberta Diabetes Institute, Department of Medical Microbiology and Immunology, University of Alberta, Edmonton, Alberta, CanadaCorresponding author (lina R. Rayât, grayat@ualberta.ca.Received 18 March 2009 and accepted 6 January 2010. Published ahead of print at http://diabetes.diabetesjournals.org on 19 January 2010. DOI: 10.2337/db09-0413.© 2010 by the American Diabetes Association. Readers may use this article as long as the work is properly cited, the use is educational and not for profit, and the work is not altered. See http://creativecommons.org/licenses/by -nc-nd/3.0/ for details.The costs of publication of this article were defrayed in part by the payment of page charges. Tfiis article must therefore be hereby marked "advertisement" in accordance with 18 U.S.C Section 1734 solely to indicate this fact.,;

  • 收录信息 美国《科学引文索引》(SCI);美国《化学文摘》(CA);
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