Mammalian Target of Rapamycin Complex 1 Suppresses Lipolysis, Stimulates Lipogenesis, and Promotes Fat Storage

Partha Chakrabarti Taylor English Jun Shi Cynthia M Smas Konstantin V Kandror

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Mammalian Target of Rapamycin Complex 1 Suppresses Lipolysis, Stimulates Lipogenesis, and Promotes Fat Storage

机译：雷帕霉素复合物1的哺乳动物目标抑制脂肪分解，刺激脂肪生成，并促进脂肪储存。

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In metazoans, target of rapamycin complex 1 (TORC1) plays the key role in nutrient- and hormone-dependent control of metabolism. However, the role of TORC1 in regulation of triglyceride storage and metabolism remains largely unknown.

机译：在后生动物中，雷帕霉素复合物1（TORC1）的靶标在营养和激素依赖性代谢控制中发挥关键作用。但是，TORC1在调节甘油三酸酯储存和代谢中的作用仍然未知。

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《Diabetes》 |2010年第4期|p.775-781|共7页
作者
Partha Chakrabarti Taylor English Jun Shi Cynthia M Smas Konstantin V Kandror;
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Partha Chakrabarti,1 Taylor English,1 Jun Shi,2 Cynthia M. Smas,3 and Konstantin V. Kandror1From the 'Boston University School of Medicine, Boston, Massachusetts, "Novartis Institutes for Biomedical Research, Cambridge, Massachusetts: and The University of Toledo College of Medicine, Toledo. Ohio.Corresponding author: Konstantin V. Kandror, kandror@biochem.bumc. bu.edu.Received 30 October 2009 and accepted 23 December 2009. Published ahead of print at http://diabetes.diabetesjournals.org on 12 January 2010. DOI: 10.2337/db09-1602.© 2010 by the American Diabetes Association. Readers may use tliis article as long as the work is properly cited, the use is educational and not for profit, and the work is not altered. See http://creativeconmions.org/hcenses/by -nc-nd/3.0/ for details.The costs of publication of this article were defrayed in part by the payment of page charges. This article must therefore Iw hereby marked "advertisement" in accordance with 18 U.S.C. Section 1734 solely to indicate this fact.,;

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收录信息美国《科学引文索引》(SCI);美国《化学文摘》(CA);
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1. Inhibition of mammalian target of rapamycin complex 1 signaling by n-3 polyunsaturated fatty acids promotes locomotor recovery after spinal cord injury [J] . Nie Jiping, Chen Jian, Yang Jianguo, Molecular medicine reports . 2018,第4aPta2期

机译：抑制哺乳动物催乳素复合物的哺乳动物靶标的N-3多不饱和脂肪酸的信号传导促进脊髓损伤后的运动恢复
2. Identification of Akt-independent Regulation of Hepatic Lipogenesis by Mammalian Target of Rapamycin (mTOR) Complex 2 [J] . Minsheng Yuan, Elizabeth Pino, Lianfeng Wu, The Journal of biological chemistry . 2012,第35期

机译：抗哺乳动物催乳素（MTOR）复合物的哺乳动物靶标鉴定Akt--T-Wormate调节肝脂肪生成
3. Insulin stimulates retinal ganglion cell dendrite regeneration through activation of the mammalian target of rapamycin complex land complex 2 [J] . Agostinone Jessica, Di Polo Adriana Investigative ophthalmology & visual science . 2016,第12期

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4. INSULINE LIKE GROWTH FACTOR-1 AND LEUCINE ACTIVATE PIG MYOGENIC SATELLITE CELLS THROUGH MAMMALIAN TARGET OF RAPAMYCIN PATHWAY [C] . L.T.Medeiros, rnJ.C.Pinto, rnE.M.de Castro, Proceedings of 53rd International Congress of Meat Science and Technology . 2007

机译：胰岛素样生长因子-1和亮氨酸通过雷帕霉素途径的哺乳动物靶标激活猪生代卫星细胞
5. Myc directly stimulates lipogenesis and suppresses fatty acid oxidation in human P493 cells [D] . Gouw, Arvin M. 2012

机译：Myc直接刺激脂肪生成并抑制人P493细胞中的脂肪酸氧化
6. Mammalian Target of Rapamycin Complex 1 Suppresses Lipolysis Stimulates Lipogenesis and Promotes Fat Storage [O] . Partha Chakrabarti, Taylor English, Jun Shi, 2010

机译：雷帕霉素复合物1的哺乳动物目标抑制脂肪分解刺激脂肪生成并促进脂肪储存。
7. Mammalian Target of Rapamycin Complex 1 Suppresses Lipolysis, Stimulates Lipogenesis, and Promotes Fat Storage [O] . Chakrabarti, Partha, English, Taylor, Shi, Jun, 2010

机译：雷帕霉素复合物1的哺乳动物目标抑制脂肪分解，刺激脂肪生成，并促进脂肪储存。

Mammalian Target of Rapamycin Complex 1 Suppresses Lipolysis, Stimulates Lipogenesis, and Promotes Fat Storage

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