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首页> 外文期刊>Diabetes >Recurrent Moderate Hypoglycemia Ameliorates Brain Damage and Cognitive Dysfunction Induced by Severe Hypoglycemia
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Recurrent Moderate Hypoglycemia Ameliorates Brain Damage and Cognitive Dysfunction Induced by Severe Hypoglycemia

机译：复发性中度低血糖可减轻严重低血糖引起的脑损伤和认知功能障碍

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摘要

Although intensive glycemic control achieved with insulin therapy increases the incidence of both moderate and severe hypoglycemia, clinical reports of cognitive impairment due to severe hypoglycemia have been highly variable. It was hypothesized that recurrent moderate hypoglycemia preconditions the brain and protects against damage caused by severe hypoglycemia.
机译：尽管通过胰岛素治疗实现严格的血糖控制可增加中度和重度低血糖的发生率，但由于严重低血糖引起的认知障碍的临床报道高度可变。据推测，反复发作的中度低血糖可预处理大脑，并防止严重的低血糖引起的损害。

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  • 来源
    《Diabetes》 |2010年第4期|p.1055-1062|共8页
  • 作者

    Erwin C Puente Julie Silverstein Adam J Bree Daniel R Musikantow David F Wozniak Susan Maloney Dorit Daphna-Iken Simon J Fisher;

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    Erwin C. Puente,1 Julie Silverstein,1 Adam J. Bree,1 Daniel R. Musikantow/ David F. Wozniak,2 Susan Maloney,2 Dorit Daphna-Iken,1 and Simon J. Fisher1,3From the 'Division of Endocrinology, Metabolism, and Lipid Research, Department of Medicine, Washington University, SL Louis, Missouri, the 2Department of Psychiatry, Washington University, St. Louis, Missouri, and the ,,Department of Cell Biology and Physiology, Washington University, St. Louis, Missouri.Corresponding author Simon Fisher, sfisher@dom.wustl.edu.Received 8 October 2009 and accepted 6 January 2010. Published ahead of print at http://diabetes.diabetesjoiirnals.org on 19 January 2010. DOl: 10.2337/db09-1495.© 2010 by the American Diabetes Association. Readers may use this article as long as the work is properly cited, the use is educational and not for profit, and the work is not altered. See http://creativecommons.org/licenses/by -nc-nd/3.0/ for details.The costs of publication of this article were defrayed in part by the payment of page charges. litis article musi therefore be hereby marked "advertisement" in accordance with 18 U.S.C. Section 17M solely to Indicate this fact.,;

  • 收录信息 美国《科学引文索引》(SCI);美国《化学文摘》(CA);
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