Updated Genetic Score Based on 34 Confirmed Type 2 Diabetes Loci Is Associated With Diabetes Incidence and Regression to Normoglycemia in the Diabetes Prevention Program

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  《Diabetes》 |2011年第4期|p.1340-1348|共9页
• 作者

  Marie-France Hivert Kathleen A Jablonski Leigh Perreault Richa Saxena Jarred B McAteer Paul W Franks Richard F Hamman Steven E Kahn Steven Haffner James B Meigs David Altshuler William C Knowler Jose C Florez;

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  Marie-France Hivert,1 Kathleen A. Jablonski,2 Leigh Perreault,3 Richa Saxena,4'5 Jarred B. McAteer,4'5 Paul W. Franks,6,7 Richard F. Hamman,8 Steven E. Kahn,9 Steven Haffner,10 the DIAGRAM Consortium,* James B. Meigs,11,12 David Altshuler,4,5,12,13,14 William C. Knowler,15 and Jose C. Florez,4,5,12,14 for the Diabetes Prevention Program Research Group*From the 1 Division of Endocrinology. Department of Medie-ine. Université de Sherbrooke. Sherbrooke, (,nichée, (miada: 2 The Biostatistics ( enter, The George Washington University, Rockville. Maryland: the 3 Department of Medicine, Division of Endocrinology, Metabolism and Diabetes, University of Colorado at Denver School of Medicine, Aurora, Colorado, dje 4 Center for Human Genetic Research, Massachusetts General Hospital. Boston. Massachusetts, the 5 Program in Medical and Population (ieneties, Broad Institute. Cambridge, Massachusetts, the 6 Department of Public Health and Clinical Medicine. Division of Medicine, Genetic Epidemiology and Clinical Research (iroup, Tinea University Hospital, Unica, Sweden, the 7 Department of Clinical Sciences, Lund University Diabetes Center. Land University, Malino, Sweden, the Department of Epidemiology, Colorado School of Public Health, University of Colorado at Denver, Aurora, Colorado, the 9 Division of Metabolism, Endocrinology and Nutrition, Veterans' Affairs Puget Sound Healtii Care System and ttie University of Washington. Seattle. Washington, the 10 Taylor College of Medicine, Houston. Texas, the 11 General Medicine Unit, Massachusetts General Hospital. Boston. .Massachusetts: die 12 Department of Medicine, Harvard Medical School, Boston, Massachusetts, die 13 Department of Genetics, Harvard Medical School, Boston, Massachusetts, the 14 Diabetes Research Center (Diabetes Unit), Department of Medicine, Massachusetts General Hospital. Boston, Massachusetts, and the 'Diabetes Epidemiology and Clinical Research Section, National Institute of Diabetes and Digestive and Kidney Diseases. Phoenix, Arizona.Corresponding author: Jose C. Florez. jcnorez@partners.org and dppniailG? biostat.bsc.gwu.edu.Received 6, August 2010 and accepted 29 December 2010.DOI 10.2337/dblO-U19. Clinical trial reg. no. NCT00004992, clinicaltrials.gov.This article contains Supplemental} Data online at http://diabetes. diabetesjounials.Org/lookup/suppi7doi:10.2:W7/dblO-1119/-/DCl.The opinions expressed are those of the investigators and do not necessarily reflect the views of the Indian Health Service or other funding agencies.*Complete lists of the members of die Diabetes Prevention Program Research Group and the DIAGRAM investigai ors are provided in the Supplementary Data© 2011 by die American Diabetes Association. Readers may use this article as long as the work is properly cited, the use is educational and not for profit, and die work is not altered. See http://creativecommons.org/licenses/by -nc-nd/:i.O/ for details.,;

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• 收录信息 美国《科学引文索引》(SCI);美国《化学文摘》(CA);
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