Proof-of-concept trial on the efficacy of sodium tungstate in human obesity

F. Hanzu; R. Gomis; M. J. Coves; J. Viaplana; M. Palomo; A. Andreu; J. Szpunar; J. Vidal

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Proof-of-concept trial on the efficacy of sodium tungstate in human obesity

机译：钨酸钠治疗肥胖症的概念验证试验

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Aim: Considering the poor long-term success of current dietary and pharmacological interventions, we aimed to evaluate the potential effect of sodium tungstate in the treatment of grade I and II obesity (ClinicalTrials.gov identifier: NCT00555074).

机译：目的：考虑到当前饮食和药物干预措施长期效果不佳，我们旨在评估钨酸钠在治疗I级和II级肥胖症中的潜在作用（ClinicalTrials.gov标识符：NCT00555074）。

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来源
《Diabetes, Obesity and Metabolism》 |2010年第11期|1013-1018|共6页
作者
F. Hanzu; R. Gomis; M. J. Coves; J. Viaplana; M. Palomo; A. Andreu; J. Szpunar; J. Vidal;
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作者单位

Endocrinology and Nutrition Department Hospital Clínic IDIBAPS Barcelona University Barcelona Spain;

CIBER de Diabetes y Enfermedades Metabólicas Asociadas (CIBERDEM) Barcelona Spain;

Hemotherapy and Hemostasia Department Hospital Clinic Barcelona University Barcelona Spain;

Laboratoire de Chimie Analytique Bio-inorganique et Environnement CNRS UMR 5254 Hélioparc France;

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原文格式 PDF
正文语种 eng
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关键词
antiobesity drug; clinical trial; phase I and II study;

机译：抗肥胖药;临床试验;I和II期研究;

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专利

1. Proof-of-concept trial on the efficacy of sodium tungstate in human obesity. [J] . Hanzu F, Gomis R, Coves MJ, Diabetes, obesity & metabolism . 2010,第11期

机译：钨酸钠对人类肥胖的功效的概念验证试验。
2. Efficacy and safety of secukinumab, a fully human anti-interleukin-17A monoclonal antibody, in patients with moderate-to-severe psoriatic arthritis: A 24-week, randomised, double-blind, placebo-controlled, phase ii proof-of-concept trial [J] . McInnesI.B., SieperJ., BraunJ., Annals of the Rheumatic Diseases: A Journal of Clinical Rheumatology and Connective Tissue Research . 2014,第2期

机译：secukinumab，一种完全的人类抗白介素17A单克隆抗体，在中度至重度银屑病关节炎患者中的疗效和安全性：为期24周，随机，双盲，安慰剂对照，II期概念验证试用
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机译：Secukinumab的疗效和安全性，一种完全人的抗白细胞介素-17A单克隆抗体，中度至严重的银屑病性关节炎患者：24周，随机，双盲，安慰剂控制，第二期概念证明审判
4. Simulated Mars-flight Sodium and Hypertension Study (SMASH Study): efficacy trial on the salt/blood pressure relationship [C] . Natalia Rakova “中、美食盐与健康”国际研讨会（International Workshop of Dietary Sodium and Human Health in China and the United States） . 2008

机译：模拟火星飞行钠和高血压研究（SMASH研究）：盐/血压关系的功效试验
5. The efficacy of a dopamine D2 agonist in treating obesity and obesity-related conditions in rodent models. [D] . Davis-McGuire, Lisa. 2006

机译：多巴胺D2激动剂在啮齿动物模型中治疗肥胖和肥胖相关疾病的功效。
6. Anti-Obesity Sodium Tungstate Treatment Triggers Axonal and Glial Plasticity in Hypothalamic Feeding Centers [O] . Marta Amigó-Correig, Sílvia Barceló-Batllori, Guadalupe Soria, 2009

机译：钨酸钠抗肥胖症治疗可触发下丘脑喂养中心的轴突和胶质可塑性
7. Efficacy and safety of secukinumab, a fully human anti-interleukin-17A monoclonal antibody, in patients with moderate-to-severe psoriatic arthritis: a 24-week, randomised, double-blind, placebo-controlled, phase II proof-of-concept trial [O] . McInnes, Iain B., Sieper, Joachim, Braun, Jürgen, 2014

机译：secukinumab，一种完全的人类抗白介素17A单克隆抗体，在中度至重度银屑病关节炎患者中的疗效和安全性：24周，随机，双盲，安慰剂对照，II期概念验证试用

Proof-of-concept trial on the efficacy of sodium tungstate in human obesity

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