Effects of endoscopic gastric plication on portal pressure gradient in a patient with nonalcoholic steatohepatitis cirrhosis

摘要

Nonalcoholic fatty liver disease is the most common cause of chronic liver disease worldwide, with the preva- lence approaching 90% in patients with obesity. Nonalco- holic steatohepatitis (NASH) is an aggressive form of nonalcoholic fatty liver diseasewith anincreased riskof pro- gressiontocirrhosis.Todate,the only treatment for NASHis lifestyle modification (LM). 1 Previous studies showed that at least 7% to 10% total weight lossis required for improvement in liver steatosis, inflammation, and fibrosis regression. 2 Nevertheless, less than 10% of patients who undergo LM achieve this threshold, leaving the majority of patients with NASH undertreated.