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Survival of silver diamine fluoride among patients treated in community dental clinics: a naturalistic study

机译:社区牙科诊所治疗患者银氟化胺的存活:自然研究

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Silver diamine fluoride (SDF) is a minimally-invasive preventive service used in the U.S. to avert and arrest caries since 2014. No studies document survival outcomes based in real world delivery. We analyzed 12-month survival outcomes of SDF applied independently or concurrently with other restorative procedures among a population receiving community dental care. We analyzed data on SDF applications from de-identified dental claims on Oregon Health Plan patients served by Advantage Dental in 2016, who had been seen in 2015 (patient n?=?2269; teeth n?=?7787). We compared survival rates of SDF alone, SDF applied with a sedative filling, and SDF with a same-day restoration. Failure was defined as a restoration or extraction of the tooth 7 to 365?days after initial application. Survival was defined as a patient returning 180 or more days after application whose tooth did not have a restoration or extraction. Differences were assessed through Wilcoxon equality of survivor function tests and log-rank equality of survivor tests to compare failure rates, Cox Proportional Hazards models to assess factors associated with survival of SDF, and Kaplan–Meier survival estimate to calculate the probability of survival over time. SDF alone had an overall survival rate of 76%. SDF placed with sedative filling and with a same-day restoration had survival rates of 50% and 84% respectively, likely reflecting treatment intent. SDF alone survived exceptionally well on primary cuspids, permanent molars, and permanent bicuspids and among patients aged 10 to 20?years, with modest variation across caries risk assessment categories. A single annual application of SDF was successful in 75% of cases. Among SDF failures on permanent dentition, more than two-thirds of teeth received a minor restoration. SDF is a minimally invasive non-aerosolizing option that prevented non-cavitated lesions and arrested early decay among community dentistry patients when applied independently or concurrently with restorative procedures. Professional organizations, policy makers, providers, and payors should broaden optional SDF use by informing clinical guidelines, reimbursement policies, and treatment decisions. Future research should address clinical, social, service delivery, workforce, and economic outcomes using diverse population-based samples, and the mechanisms underlying single application success and caries prevention potential.
机译:银二胺氟化物(SDF)是在美国以来的微创预防服务,自2014年以来为避免和逮捕龋齿。没有研究基于现实世界交付的求生存结果。我们分析了在接受社区牙科护理的人口中独立或同时应用的SDF的12个月生存结果。我们分析了2016年优势牙科牙科牙科牙科牙科患者的去识别牙科索赔的SDF应用数据,2015年(患者N?= 2269;牙齿N?7787)。我们将SDF的存活率进行了比较,SDF施用镇静填充,以及具有同日恢复的SDF。失败被定义为牙齿7至365的恢复或提取初始应用后的天数。存活率被定义为患者在牙齿没有恢复或提取的施用后返回180天或更多天。通过幸存者函数试验的威尔克森平等评估差异,幸存者试验的对数平等来比较失败率,Cox比例危险模型,评估与SDF的存活相关的因素,以及Kaplan-Meier存活估计,以计算随着时间的推移生存的概率。 SDF单独的总生存率为76%。 SDF与镇静剂灌装和同日恢复放置,分别存在50%和84%的生存率,可能反映治疗意图。单独的SDF在初级囊,永久臼齿和永久性双裂性和长期患者中幸存下来,以及10到20岁的患者,龋齿风险评估类别的适度变化。单一的SDF应用程序在75%的情况下成功。在永久牙列的SDF失败中,超过三分之二的牙齿接受了次要修复。 SDF是一种微创非雾化选择,可防止非空腔病变,并在独立或与恢复程序同时申请时,妇女牙科患者的早期衰变。专业组织,政策制定者,提供商和付款人应通过通知临床指南,报销政策和治疗决策来扩大可选的SDF使用。未来的研究应使用不同的基于人口的样本来解决临床,社会,服务,劳动力和经济结果,以及单一应用成功的机制和龋齿预防潜力。

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