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Research Based on Multimodal Deep Feature Fusion for the Auxiliary Diagnosis Model of Infectious Respiratory Diseases

机译:基于多模式深度融合对传染性呼吸疾病辅助诊断模型的研究

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Pulmonary infection is a common clinical respiratory tract infectious disease with a high incidence rate and a severe mortality rate as high as 30%–50%, which seriously threatens human life and health. Accurate and timely anti-infective treatment is the key to improving the cure rate. NGS technology provides a new, fast, and accurate method for pathogenic diagnosis, which can provide effective clues to the clinic, but determining the true pathogenic bacteria is a problem that needs to be solved urgently, and a comprehensive judgment must be made by the clinician combining the laboratory results, clinical information, and epidemiology. This paper intends to effectively collect and process the missing values of NGS data, clinical manifestations, laboratory test results, imaging test results, and other multimodal data of patients with infectious respiratory diseases. It also studies the deep feature fusion algorithm of multimodal data, couples the private and shared features of different modal data of infectious respiratory diseases, and digs into the hidden information of different modalities to obtain efficient and robust shared features that are conducive to auxiliary diagnosis. The establishment of an auxiliary diagnosis model for the infectious respiratory diseases can intelligentize and automate the diagnosis process of infectious respiratory, which has important significance and application value when applied to clinical practice.
机译:肺部感染是一种常见的临床呼吸道传染病,发病率高,严重的死亡率高达30%-50%,这严重威胁着人的生命和健康。准确且及时的抗感染性治疗是提高治愈率的关键。 NGS技术提供了一种新的,快速,准确的致病性诊断方法,可以为临床提供有效的线索,但确定真正的致病细菌是迫切需要解决的问题,临床医生必须进行全面判断结合实验室结果,临床信息和流行病学。本文打算有效地收集和处理发病呼吸疾病患者的NGS数据,临床表现,实验室测试结果,成像测试结果和其他多模式数据的缺失值。它还研究了多式联数据的深度特征融合算法,耦合不同模态数据的私有和共享特征,不同的传染性呼吸疾病数据,并挖掘不同方式的隐藏信息,以获得有利于辅助诊断的有效和强大的共享特征。建立传染性呼吸系统疾病的辅助诊断模型可以智能化和自动化传染性呼吸的诊断过程,当应用于临床实践时具有重要意义和应用价值。

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