Correlation of Body Mass Index, Mean Arterial Pressure with Peak Expiratory Flow Rate in Healthy Individuals- A Descriptive Study

摘要

Modern lifestyle has resulted in an increased prevalence of cardiovascular and respiratory diseases along with being overweight.An interaction between the three factors has also been demonstrated.Aim: The study aimed to assess the relationship of Body Mass Index (BMI), Mean Arterial Pressure (MAP) and Peak Expiratory Flow Rate (PEFR) in healthy individuals.Materials and Methods: This cross-sectional, observational study was done in the Department of Physiology, KGMU, Lucknow from 30th July 2019 to 30th July 2020.Forty healthy individuals, aged 18-35 years were assessed for height, weight, blood pressure and spirometric parameter of PEFR.PEFR was chosen as it was a reliable representative of airways functioning.PEFR reflects proximal airway calibre changes which might be due to effect of airway geometry.A correlation test was run to test the relation between BMI and PEFR and MAP and PEFR.Results: A weak negative correlation (r=-0.136) was noted between BMI and PEFR indicating that as BMI increased, PEFR compromised.A linear correlation was observed between MAP and PEFR.Conclusion: The present study confirms a weak association of BMI with PEFR, however strong association of MAP with PEFR was noticed.